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Czw 20:26, 31 Mar 2011 |
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e054831577
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Dołączył: 17 Gru 2010
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Skąd: England
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| Temat postu: Morphine on rat dorsal root ganglia and spinal cor |
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Morphine on rat dorsal root ganglia and spinal cord fluoride resistant acid phosphatase activity of
fpeptide-comainingWlm ~ ryaHerent16 Zhongshan Medical School photo (AcadJSUMS) 1995,16 (1) neuronsafterneonatalcapsaicin. Neurosei, 198L, 6 (4) l1923gFitzgeraldM. Capsai ~ inandsensoryneurons - areview. Pain, 1983, l5 (2) t1O9L0 Zhao Zhiqi . Blocks the modulation of pain . In: Ji-Sheng Han ( Editor ). Neuroscience Program . Beijing: Beijing Medical University and Peking Union Medical College Press Union station , 1993.635I1JessellTM. IversenLL. Opiateanalgesicsin-hibitsubstancePreleasefromrattri ~ emlnalnucleas. Nature, l977.268 (5620) l549 (1994.03.15 Received 1994.07-21 Revised ) EFFECTSoFMoRPHINEoNFLUoRIDE-RESISTANTACIDPH0SPHATASE (FRAP) ACTIVITYINDoRSALRooTGANGLIoNANDSPINALCoRDoFRATZengYuanshan (DepartmentolHistologyandEmbryology, SunYet-SenUnivershyofMedicalSciences} Guangzhou,[link widoczny dla zalogowanych], 510089) Ratsweremadedependentonmorphinebyrepeatedinjectionwithincreasingdosageofmorphine. Onthebasisofmorphinedependentrats, thechangesofFRAPactivityatthesomeofsmallsizedneuronsofdorsalrOOtganglion (DRG) anditsterminalofprimaryaffer-entfiberswereobservedandmeasuredbyhistochemistrytechniqueandmicrocomputerimagefinslysersystem. Theresultsshowedasbelow: ThereWSSFRAPpositivesomaofDRGsinailsizedneuronsofmorphinerats, whichwassignificantlyweakerthanthatofcontrolrats. FRAPintensityofL3, L4, LsspinallaminalIWSSobviouslyweakerofmorphineratsaswel1. FRAPpositiveareaofspinallaminaIofbothsidesshowedsymmetryofmorphinerats, whichdecreasedto9Oascomparedwithcontrolrats. Itindicatesthatmorphinemayinhib-itthesynthesisofFRAPnneuronsofDRG, SOthatFRAPactivitydecreasesinthesomaofDRGsmallsizedneuron ~ andintheterminalofprimaryafferentfibersoflamina Ⅱ. Subjectheadingsmorphine; fluoride-resistant; acidphosphatase; dorsalrootgan-glion, spinsIlamlna Ⅱ; rats
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