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Wysłany: Nie 0:37, 13 Mar 2011
Temat postu: Internet and drug safety _6013
Internet and drug safety
And so on. Encrypted transfer of data in epidemiology,
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, pharmacovigilance studies,
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, and other fields still under development, the next few years will be great development in this area. 6 of the Internet in drug safety data in the application of 6.1 to send Internet data has been implemented timely medical care, fast delivery and many research institutions, the government can provide for the logged on user data. Currently,
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, software developers, advertisers, and so are committed to developing new technology to direct users to different requirements of different data that provide these technologies help, people can more quickly and accurately find the data they need to download the file allows users to easily access large amounts of data, or even download the entire database, and then analyzed with the corresponding software package to transfer data,
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, but the Internet also has its negative aspects: (1) data can be intentionally or unintentionally misuse and misinterpretation; ( 2) The data can be replaced, and then sent. The recipient does not know the data changes; (3) data integrity -282 · j (J, rMedical'ient draw firm scientific conclusions, the data transfer should be considered after the side effects are beneficial to public health or just cause people to question the safety of drug advertising and promotion on the Internet is best to have some of the corresponding law. 6.2 Data collection on the Internet, the side effects of data collection is easier to control. The wider range of networks, encryption and other means of protection, the data can be easily and quickly in the government asked the company or between the Government and the clinical observer and the observed passed between. With the implementation of new laws, confidentiality requirements may be higher, which will also collect data on Arab and share a 6.3 pass further restrictions on the Internet has greatly changed flood connect people's means of communication make Online chat allows people or groups of one to one to one or more languages to communicate in real time with the use of e-mail message can be sent simultaneously to multiple recipients. Internet's largest use is in the government or between government and the cooperation safety data exchange between those. If enacted by the ICH M1, M2 and E2B standard, then the security of data transmission capacity will greatly enhance the Internet is likely to change the way drug safety studies. It will change in addition to data collection, transmission and communication, are more likely to improve data analysis capabilities,
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, which draw conclusions about medicine safety, and promote public health research to improve pharmacovigilance will also be a huge change (199905,10 Received) Pseudomonas aeruginosa The active efflux system and resistance to Review Leftist Wang Yufeng Yao Tianjue Reviser (Chinese Medical Sciences and Peking Union Medical University, Anhui Institute of Medicinal Biotechnology, Beijing 1O005m) Summary of Pseudomonas aeruginosa (Yin pathogenic infection conditions, who often infected with cancer, glass, burn patients and other immunocompromised patients, many different physical and chemical properties of its highly resistant to the drugs, the active efflux system in resistance to play a major role in this paper, the Green pus bacillus found active efflux pumps, type, mechanism of resistance to antibiotics and other aspects of progress. Keywords Pseudomonas aeruginosa; efflux system; drug resistance of P. aeruginosa (PseudomonasaeruginosaJ, also known as Pseudomonas aeruginosa, is an important opportunistic pathogen of nosocomial infections, often infected with cancer patients, burn patients and other immunocompromised patients, and because of its innate and acquired drug resistance, clinical treatment very difficult, once infected, mortality is high. a variety of different types of Pseudomonas aeruginosa highly resistant to antibiotics, the resistance mechanism is very complex: P. aeruginosa outer membrane permeability of low permeability of its non-specific E. coli is only 02 ~ 1 ; when P. aeruginosa after contact with antibiotics, can produce antibiotic modifying enzymes (such as penicillin hydrolase); reduce the sensitivity of antibiotic action sites; by lack of channel protein (porin) decreased permeability of antibiotics; in recent years study found that there is a Pseudomonas aeruginosa efflux in a variety of active substances in complex discharge system: its multiple drug resistance in Pseudomonas aeruginosa plays an important role. This paper on the active efflux system of Pseudomonas aeruginosa and MDR reviewed the research progress. 1 drug resistance profiles of Pseudomonas aeruginosa multidrug resistance of bacteria is often resistant to the occurrence of the nature of particles (R plasmid) and with a variety of different resistance determinants (determinants) caused . In G-bacteria in the outer membrane barrier of the National Natural Science Foundation of someone to deliver aid projects - ~ -39,770,018
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