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Dołączył: 17 Gru 2010
Posty: 604
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Ostrzeżeń: 0/5 Skąd: England
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Temat postu: Angina pectoris with normal coronary arteries in p |
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Patients with angina pectoris with normal coronary arteries of myocardial blood flow distribution
/ / Wwwehil'Mnfogoverdpefiodi ~ antihypertensive effect of nifedipine controlled release trough / peak ratio of clinical studies have been heroes Yi Li Jie Mai Liao Wei Xing Tan Kok Wai Chun Wang (Zhongshan Medical School to go the First Affiliated Hospital of Guangzhou 510O80) the purpose of calculation of release of nitric benzene horizon antihypertensive effect of the treatment of primary hypertension trough / peak ratio (T / PR) and the best way to smooth the drug index (s1). Method of mild to moderate essential hypertension in 32 patients, each morning serving Zhu release nifedipine (nifedipineGITS) 30mg, made after pre-treatment ambulatory blood pressure monitoring and 4wk deleted. 2h individual sub-cut method to calculate the whole group and T / PR and calculate the drug sI. Results 4wk after treatment blood pressure and ambulatory blood pressure even lower rate,[link widoczny dla zalogowanych], respectively (24 ± 12) / (12 ± mmHg and (14.5 ± 39) / (11.2 ± 3.1) nmfl-ig; Calculation of the individual's systolic and diastolic blood T 『PR were 0.65 ± 0.23 and 0.66 ± 025, and the whole maggot 0.62 and 0.68, respectively laws; systolic and diastolic drug Pressure S1 3.74 and 3.77, respectively. Conclusion release nifedipine can be smooth and effective antihypertensive 24h; its role in blood pressure steady by T / PR, and SJ reflected. Key words Hypertension Gu Sui peak ratio index of ambulatory blood pressure level controlled-release nifedipine CLC IO72, 41988, the U.S. Food and Drug Administration (FDA) raised blood pressure effects of antihypertensive drugs trough / peak ratio (troughtopeakratio, T 『I] R) since the concept, clinical studies carried out a more specific methods, but more concentrated in their metabolic characteristics with long-lasting effect of the drug. We used ambulatory blood pressure in 2000-12 topiramate Received, 20g102 ~ 14 Revised monitoring (ABPM) technique to study the antihypertensive effect of nifedipine controlled release to calculate the antihypertensive effect of 1 sI) to evaluate the antihypertensive effect of 1 Materials and methods 1.1 object in July 1998 ~ June 2000 diagnosed with mild to moderate hypertensive patients, in line with WHO / ~ H1993 diagnostic criteria of hypertension, completed the study were a total of 32 cases. L8 were male,[link widoczny dla zalogowanych], female l4, aged 48 to 73 years, mean (60.7 ± 10.4) years, duration of l ~ l4 years, the average (6.3 ± 4. years; mild l2 cases moderate in 20 cases. I of 23 cases,[link widoczny dla zalogowanych], Ⅱ in 8 cases, Ⅲ method of choice in patients with 1.2 l patients stop taking the drugs affect blood pressure after 2wk, such as blood pressure even while still meet the diagnostic criteria for ambulatory blood pressure monitoring, then give controlled release of nifedipine (brand name Adalat, Bayer product) 30nag, 1 Japan 1 (8AM) oral, 4wk after the review of ambulatory blood pressure. Even blood pressure: use of a calibrated standard mercury column sphygmomanometer + sitting right upper limb blood pressure measurement, provides time for the 8AM. Ambulatory blood pressure monitoring: U.S. A ~ cutracker Ⅱ type of ambulatory blood pressure monitoring (SuntechMedicalInc), left upper limb blood pressure measurements, since 8PaM 8AM the following day a total of 24h, the day every 20rain, 30rain automatic measurements per night 1. 1.3 Statistical calculation of the individual first hour ambulatory blood pressure (ABP: x),[link widoczny dla zalogowanych], 2h for a period of time taken to determine the peak, calculated a change. Were measured in all patients before the treadmill exercise dance experience (Bruce solution), there will be movement or the next level anterior oblique sr depression in patients with type distribution in the x syndrome group (x New Zealand, 5 males and 6 females. The average age 52 years old),[link widoczny dla zalogowanych], no s1 'loyal segment changes as control group (7 males and 7 females, mean age 46 years). Base and atrial pacing (150bpm, a total of 3rnin) measured immediately after the anterior descending branch of the regional myocardial membrane and the Friends of the order of subepicardial ratio (ED / EP). Results can be induced by atrial pacing in patients with chest pain for all x syndrome and ST segment depression, while the control group was negative. Immediately after pacing in patients with X syndrome ED / EP ratio was significantly lower (0,98 ± 010 ~ 0,76 ± 017, P <0.01) + no change in the control group stripping. Conclusion exercise stress state lead to abnormal distribution of myocardial blood flow in patients with X syndrome, chest pain and ST segment depression in the main reason. Key words Muscle cramps coronary blood flow distribution muscle Wing ultrasound imaging CLC R6.54.2
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