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Temat postu: Ugg schuhe Immunomodulatory effects of Chinese her |
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Immunomodulatory effects of Chinese herbal medicine (II)
2.3 herbal ingredients on the role of natural killer cells to promote natural killer (NK) cells are the body's immune response in a cell can kill the tumor cells in vivo and virus infected cells, immune surveillance and anti-play The role of infection, is the body of a non-specific immunity, which exists in the serum and tissues, in which the spleen most. LBP can enhance the cytotoxic activity of NK cells and increased white blood cell count, while on cyclophosphamide induced cytotoxic activity of NK cells reduced the role of a recovery. Huang Jing et al [15] that the fermentation of Ganoderma lucidum polysaccharide extract can significantly improve NK cell activity and lymphocyte transformation rate, and maintain a certain level. Kongxiang Feng et al [16] reported that 35 day old chicks APS NK cells significantly enhanced the role of studies have shown that Epimedium - propolis mixture on chicken ability of NK cells in natural killer significant role in promoting. 2.4 RBC immune herbal ingredients promote feeding polysaccharides, lentinan chicks, the red blood cells detected in the majority of E-C3bR times higher than the control chicks; Astragalus polysaccharide and lentinan group chickens in most of the testing period of E-IC rosette were lower than control chicks, indicating that APS and lentinan on immune function in RBC increased with the secondary role, while ABPS normal and immunocompromised mice on immune function of red blood cells, the results show that the ABPS can significantly improve normal and immunocompromised mice red blood cell C3b receptor rosette rate of red blood cell adhesion binding immune complex rosette binding proved ABPS, and immunosuppression can enhance the normal immune function in mice. It was also reported LBP normal mice significantly increased erythrocyte complement receptor rosette and rosette rate of red blood cell immune products, enhance immune function in mice, Astragalus, Ganoderma lucidum, pig tea, Codonopsis, angelica, TCS and other polysaccharides can regulate traditional Chinese medicine cell C3b receptor, E-C3bR rosette rate, and enhance immune function. Zhang et al [17] reported that delphinidin Department to improve the Newcastle disease Ⅰ, Ⅱ, Department of vaccine antibody titers, increased red blood cell C3bR, TC and BC levels, and promote the thymus,[link widoczny dla zalogowanych], spleen and bursa of development than those in control group. Yupingfengsan also reduce the number of mouse Lyt-2 cells, so that the relative enhance T cell immunity, Yu Ping Feng San Jia Wei of normal mice and injected with hydrocortisone induced immunosuppression in mice can enhance rosette formation cells, increased lymphocyte percentage increase caused by injection of cyclophosphamide in normal mice and T-lymphocytes in immunodeficient mice [18]. 3 many immunosuppressive effects herbal ingredients polysaccharides inhibit tumor cell growth and enhance immune function. At present, that the mechanism of the antitumor effect of polysaccharides is the role of the tumor cells were cytotoxic to improve the host immune function, as well as anti-vascular activity of inhibitors play a role in tumor recurrence. Angelica polysaccharide (AP) in the promotion of non-specific immunity in mice enhanced the same time, humoral immunity is also a strong inhibitory effect, not only in normal mice serum hemolysin IgG, IgM strongly inhibited the formation, but also showed synergy with CTX, which may be angelica polysaccharide (AP) on the role of different lymphocyte subsets in different, or the total sugar composition of different molecular weight due to the different roles played. In vivo application of Angelica polysaccharide (AP) not only can burn spleen index and thymus index back to normal, but also correct the burned mice T lymphocyte transformation, suppressor T cells (TS) inhibitory activity, IL-2 production and inhibited IL-2R expression in the state, so that macrophages secreted IL-2 inhibition of epidermal growth factor (PGF) synthesis,[link widoczny dla zalogowanych], but also can enhance the immune chickens of Newcastle disease vaccine, Department Ⅳ antibody titers. Lanqin injection good for ConA-induced porcine peripheral blood T lymphocyte function, different doses of Lanqin injection on mouse peritoneal macrophages with a bi-directional regulation of neutral red [19]. Fucoidan can significantly inhibit the formation of experimental arterial thrombosis, venous thrombosis in rats also significantly inhibited in a dose dependent manner. Ganoderma lucidum polysaccharides against thrombosis can significantly reduce the thrombus weight, reduce the thrombus length; was significantly prolonged partial thromboplastin time, platelet aggregation, but had no effect on platelet count. Ginseng polysaccharide combined with IL-2 in vivo anti-tumor and have a strong inhibitory effect of ginseng polysaccharide itself or may be induced by cytokines can enhance T cell IL-2 对, NK cells and stimulation of tumor infiltrating lymphocytes to activate these cells, but also for killing tumor cells play an active role. Grifola frondosa polysaccharide fermentation broth to the S180 tumor-bearing mice with 100 mg / (kg · d) intragastric administration of 11 d, on the S180 has significant tumor inhibitory effect, and that Polysaccharide showed anti-tumor activity dual role, that can directly kill cancer cells Grifola frondosa polysaccharide, but also improve the body's immunity. 4 prospect herbal active ingredients present,[link widoczny dla zalogowanych], the immune pharmacological action of Chinese herbal medicine in many ways,[link widoczny dla zalogowanych], not mature at the cellular level and molecular level to clarify the issues to be more immune to some extent restricted the study of Chinese herbal medicine depth. Only a more profound understanding of the mechanism of pharmacological effects of Chinese herbal immune to rational use of drugs for clinical screening and to provide assurance. With in-depth research, screening of Chinese herbal medicine has a role in promoting immunization, isolation, and the compatibility of active ingredients extracted more reasonable compound, has become an important research direction, it can be used as the vaccine immunity with the use of prescription and to improve vaccine effect. All information in this column are the original site, reproduced please specify \ More articles related to topics:
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