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| Temat postu: tory burch sale Active hepatitis patients with cir |
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Active hepatitis patients with cirrhosis of collagen type IV and laminin levels ...
Liver fibrosis is a real dirty extracellular matrix of connective tissue proliferation. Main component is collagen,[link widoczny dla zalogowanych], glycoproteins and proteoglycans increase the results. Is an important cause of portal hypertension of liver pathological features, is currently one of the problems of liver disease research. After our 30 patients with active hepatitis patients with cirrhosis of the original type Ⅳ I Min (IV-C) laminin (LN) content and degree of correlation between esophageal varices analyzed a case selection in this group of 30 patients 23 males and 7 females. The average age of 57.2 years (44 ~ 75 years). All became ill and are in line with 1990 (Shanghai) of the Sixth National Conference on Viral Hepatitis revised diagnostic criteria for cirrhosis type plug standard action, of which 9 cases of liver puncture biopsy card feast. All patients underwent gastroscopy electronics. Esophageal varices (EV) diagnosis from light to heavy into I ~ Ⅳ degree, which I in 3 cases,[link widoczny dla zalogowanych], Ⅱ degree in 7 cases,[link widoczny dla zalogowanych], Ⅲ degree of ll cases, Ⅳ degree of 9 cases of 20 healthy blood donors detected down to the normal control group: 2 Detection of type Ⅳ collagen and laminin in solid one-step sandwich enzyme immunoassay method. Ⅳ a c mouse anti-human monoclonal antibody kit was purchased from Fuji Chemical Industry Company of Japan; pure LN kit purchased from Sig-ma company, goat anti-rabbit horseradish peroxidase by the Beijing Academy of Military Medical Biology (Victoria) Corporation available. Buju operation type according to kit instructions GFIO0 Olin Olympus gastroscope produced by the Japanese. 3 | Vision fruit active hepatitis patients with cirrhosis type Ⅳ collagen. LN determination,[link widoczny dla zalogowanych], and the normal control group. f test method, P all <0.001. Table l. The degree of esophageal varices and serum Ⅳ a C. The correlation between LN. Correlation analysis of measurement data using linear correlation and regression methods: the degree of esophageal varices and serum C Ⅳ a significant positive correlation (r: 0.8910, P <0.01), but also a positive correlation with LN (r = 0. 8032, P <0.01). Serum type Ⅳ collagen wrapped LN l ■ 4 discussion with diagnosis of esophageal varices in cirrhotic portal hypertension is a reliable indicator. Endoscopy can accurately determine the extent of varicose and forecasting interstitial hemorrhage sinusoidal liver cells formed within the basement membrane collagen and its component n increased levels of laminin. Reflect the activities and the degree of liver fibrosis, liver fibrosis is an important reason for the formation of portal hypertension and pathological features. We detected 30 cases of hospitalized hepatitis patients with cirrhosis inserted mobility Ⅳ LN content in the original cavity, endoscopy of their degree of esophageal varices, showed that IV-C, LN levels and healthy blood donors compared with normal controls was significant differences (P <0.001), consistent with the results of pathological examination Ⅳ KO liver cells to slowly move a c content of liver of a cirrhotic liver, including a slow increase of the order of: This article focuses on the extent of esophageal varices and serum Ⅳ collagen, LN level correlation was found between serum levels of esophageal varices Ⅳ a C, L content was a significant positive correlation (r = 0.8910.P <0.01 and r = 08032, P <0 【J1) shows the degree of esophageal varices with a serum Ⅳ C, LN content increased and aggravated. Also in line 9 down liver biopsy pathological changes in connective tissue. Degree and extent of esophageal varices in cirrhosis. Bleeding is closely related to I = 30 shows the degree of endoscopic esophageal varices, and no bleeding, generally good; Ⅱ mild degree of gastric varices associated with inflammation of the stomach, revolves film 3 (3 / 7), ascites in 2 cases, no bleeding; Ⅲ ~ Ⅳ degree of complications, Ⅲ degree of bleeding accounted for 64% (7 / 11); Ⅳ degree of hemorrhage in 88% (8 / 9). Can ask the l ~ 2 times there had been bleeding history have 2 patients in the serum fibrosis markers IV-c. LN repeatedly detected, early cirrhosis patients Ⅳ a C, LN level is not treated with the decline in the recovery of liver function. But increased, which may be the progression of liver fibrosis and its continued. From the above analysis. We believe that serum collagen type Ⅳ, LN levels not only reflect the degree of liver fibrosis, reflecting the degree of portal hypertension, cirrhosis of the liver is also forecast an effective indicator of upper gastrointestinal bleeding. Because liver biopsy because of their traumatic life masts, the puncture site in patients with difficult to accept limitations and can not be universal, in order to avoid false-positive cirrhosis of the liver, should be continued in serum markers of liver fibrosis testing for clinical decision to provide more accurate and comprehensive liver fibrosis. Author: People's Liberation Army 148 Hospital, Zibo, Shandong 255300 March 1996 2 May 10 closing prayer r Revised
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