Oxygen and renal metabolism of _1914 -

e054831577

Oxygen and renal metabolism of

Inhibitory receptor,[link widoczny dla zalogowanych], reducing adenylyl cyclase activity to reduce cellular transport. When the concentration of 1Ozamo | lL, the adenosine significantly lower section of medullary thick ascending limb cell metabolism and transport related activities. And adenosine and its analogues significantly enhanced tube feedback. Therefore,[link widoczny dla zalogowanych], in ischemia,[link widoczny dla zalogowanych], the release of adenosine from anoxic damage in the prevention of medullary play the following roles: (1) straight through the small tube to improve blood flow to increase oxygen delivery. (2) reduce the transport section of medullary thick ascending limb. (3) tube through enhanced feedback and reduce the renal cortical blood flow decreased GFR,[link widoczny dla zalogowanych], to further reduce the active transport. To renal medullary interstitial infusion of adenosine can increase the medulla po, decreased renal cortical blood flow. ARF in experimental animal models, with the adenosine antagonist can increase GFR. High concentrations of NO in the medulla,[link widoczny dla zalogowanych], inhibit NO synthase reduces medullary pO. NO effects may be bidirectional, and can increase the blood flow and reduces direct mTALs tubular active transport. In hemolysis and rhabdomyolysis, the high iron released into the blood circulation in hemoglobin, increased susceptibility to kidney ARF, in part because a combination of hemin intrarenal NO mouth. 6 kidney p0 determination of non-invasive magnetic resonance imaging technique is a repeatable, non-invasive determination of skin in different parts of pO2 coral quality approach. The principle is the use of deoxy hemoglobin and oxyhemoglobin magnetic specific differences _l. Jing loop diuretic furosemide in humans can increase the medulla without changing the cortical oxygen pressure po, on the contrary, the proximal tubule diuretic acetazolamide on the role of the cortex and medulla of the p02 small. Recently found that a diuretic can increase the medulla by p02, this effect is more obvious in the young than the old, the result is consistent with the following point of view, the diuretic urine PGE2 can promote the secretion of young and old no such effect ]. Reflected in the protection against hypoxic damage in the kidney the role of the age.

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