MAC Cosmetics UK Quantitative ultrastructure of li -

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Quantitative ultrastructure of liver sinusoidal endothelial cells

Cell was damaged area, the appearance of increased endothelial cell morphological changes (Figure 3), increased shaped nuclei, cytoplasm osteoporosis,[link widoczny dla zalogowanych], edema, dense cytoplasm is easy to see-like inclusion bodies (Densebodies). The round shape for the class,[link widoczny dla zalogowanych], ranging from a few to a dozen, surrounded by a single layer, about the size of 1 ~ 2m,[link widoczny dla zalogowanych], dense bodies can be seen between the emblem of vesicles, some vesicles may have fused with the trend of dense bodies (Figure 4). Endothelial cells toward dieldrin increased the gap at the fibrous material, and a small amount of tilting the formation of the basement membrane. 2.4 Quantitative analysis of endothelial cells by image analysis, endothelial cells measured parameters in different groups, and endothelial cells form dense inclusions determination to do less. Gray-scale image analysis system from 0 to 255 in Table 1. Table 1 The quantitative study measured endothelial cell morphology (soil S) endothelial cells in an area of dense bodies were 0.94 ± 0.46m, the circumference of 4.38 ± 1.67 / ~ m, the average diameter of 1.14 ± 0.32. ~ M, the shape factor of 0.80 ± 0.11,[link widoczny dla zalogowanych], mean gray level of 191 ± l4.17. 3 discuss the sinusoidal endothelial cells endothelial cells found in the emergence of liver cell lesions similar to changes observed were consistent with this article. caused by the different etiology of liver disease, changes in endothelial cells is the same, but with the positioning of different regional inflammatory response in the function of endothelial cells were resting state and active state. We believe that endothelial cells from resting into active state, may be pathogenic factor in liver cell injury is also violated both sinusoidal endothelial cells, the endothelial cells to form active compensatory proliferation. increases fall into the sinus endothelial cells, the blocked sinuses where exacerbated by the blood circulation disorder. tests showed that morphometric study: functional active area, and other indicators of endothelial cells was significantly greater than resting endothelial cells (P <0.001) also confirmed the emergence of active endothelial cells to determine the damage to liver tissue is very meaningful. sinusoidal endothelial cells showed dense inclusions is a prominent activity of endothelial cells to change. dense bodies about the size of 1.um, by a single layer wrapping, containing homogeneous high electron density like material. Shiniehi so that inclusions are resistant to trypsin in the digestion of protein substances. In our observation, dense inclusion body (Densebodies) almost without exception, appears in the Each activity of endothelial cells, the number appears more or less, there were more endothelial cells to mutate more pronounced, the cytoplasm seems to be loose, disintegrating state of endothelial cells seems to be a non-reversible change. on the dense bodies the source is still no uniform understanding. We observed micro-vesicles in close contact with the dense bodies form, the combination seems to be fused at the performance. in a highly active endothelial cells in a variety of micro-vesicles often appeared in large numbers, some large bubble cloud flocculent substances increased and showed high electron density, some vesicles are similar to the dense bodies. When the activity of endothelial cell function in the completion of endocytosis and iron in blood proteins and other substances can easily enter with the micro-vesicles endothelial cells.
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