Iodine excess on growth and development of rat off -

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Iodine excess on growth and development of rat offspring

04-4.0210H10.1214-0.0350.1514-0.0470.2464-0.0429.764-2.4950H10.1564-0.0440.192 ± 0.0470.2554-0.04610.26 ± 1.08100H10.1074-0.041O. 1384-0.028 'O. 1984-0.030 * * 7.174-1.82 'Note: The iodine group and iodine group (NI),[link widoczny dla zalogowanych], compared,[link widoczny dla zalogowanych], P (0.05. A P <0.01. Table 9 days in each group 6O age weight of major organs offspring (±) group of thoracic hydrazone (g) Spleen (g) Kidney (g) adrenal (ms) N10.531 ± 0.1590.8314-0.080.8314-0.12647. 214-l1.895H10.4554-0.0780.8354-0.2210.8894-0.247 · 43.964-6.3210H10.5154-0.0900.8294-0.1800.8774-0.12246. 784-6.4550H10.5324-0.0930.6864-0.1470.8114-0.12448.424-5.851OOH10.4014-0.122 '0 .6214-0.183 · 0.7054-0. 115.38 .244-9.63 t Note: the iodine group and iodine group (N1) than, 'P (o.05. 3 discussed in the animal experiments, Hou-Min Yang birth certificate Ziyang iodine group growth significant delay in development, but most animal studies found that iodine intake end and the clear relationship between body weight, and individual results also observed in iodine animal weight than the control group. iodine and iodine as whether the growth of offspring development, has not been determined. the experiments on l, 2O, 60 day-old offspring body weight, body length, tail length, hind limb length and the brain and major organs of the dynamic changes in weight observed that the iodine group 1 day old pups after birth weight, length, tail length, hind legs are long compared with the NI group increased slightly, but not statistically significant, but with the water fed with iodine time in 20 days of age, The iodine group offspring weight and length, tail length, hind limb length compared with the NI group showed different degrees of retardation, in 6O days, this is more obvious behind. day-old offspring by different observation of the major organ weight was found on day 1, the iodine group when compared with the NI group no significant decrease, but with the time of drinking water iodine in 20 days and 60 days of age, the iodine group compared with the NI main organs have different levels of reduction, especially 100HI group of the most obvious. iodine is the main raw material for synthesis of thyroid hormone, growth hormone exists in the case of thyroid hormone not only mature but also to promote bone The longitudinal growth of J. 60 day old offspring of serum thyroid hormone measurements showed that the iodine excess groups decreased thyroid hormone levels. 50HI and 100HI group was lower than NI group, 100HI group A was significantly lower state. Therefore, this study suggests that long-term iodine excess offspring caused by growth retardation is due to the lower level of thyroid hormone. iodine excess will affect the growth of rat offspring, and the mechanism may be related to iodine induced hypothyroidism, but the rats Iodine has strong tolerance, this study shows that when the normal intake of iodine intake of less than 5O times, it will not significantly affect the next generation of growth and development.

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