Han nationality of Zhejiang myeloid antigen gene f -

e054831577

Zhe Han nationality population gene frequency of myeloid antigen DA

etterquisrHHLADRtypingbyPC. Rm ~ pliflcatlon, chuspecificprir ~ (~ CR-SSP) in2hours: ∞ atterrm-tiretose ~ olngiDRtypinginclmJpracticeincludingdor ~ orclplentmatchingincada ~ erictr ~ sp] antatlonTissueAndgerts. 1992 {39:2253 M. ChenCC,, WangCL, etat. FrequenciesofnemR】 philspe-ciflcattigtn ~ snDChineseinTaiwanVox, 1994; 66:247 (1999-08-15 Received, 20004} 2-29 Revised) edited this article: Shang Yun / 1L, l minute plasma exchange combined with chemotherapy in treatment of multiple myeloma. 3ool3 ink Shanxi Tumor Hospital Fort Qiao Hong Guo Runlian cattle mullet _ An / r) 7 bow bow - a ,,'/> Keywords Keywords R733.3 plasma exchange in China falling into the lotus of a blue wall of the main fall R457 ink .14 R403 8O years since since the invention of the blood cell separator, plasma exchange (PE) in multiple areas of disease treatment has been widely used, especially for multiple myeloma (MM), refractory and recurrent cases, with chemotherapy, and achieved a certain effect. Comprehensive sets of the author since 1984 8 of 43 cases reported in the literature a total of 119 IrE, in order to be useful for the treatment of MM. 1 Materials and methods 11 cases of hospital source application IrE treatment MM8 side, refer to domestic on-line information retrieval, information science and technology in China by the Chinese scientific and technological journals TRIP system and Version databases PE from 1984 to 1997 the report of the treatment were 43 cases of MM, immunophenotyping IG17 cases, IgAt7 cases, light chain 2 cases and not recorded in 7 cases. The oldest 72 years old. PE for the first visit in 23 cases,[link widoczny dla zalogowanych], chemotherapy t7 cases,[link widoczny dla zalogowanych], not recorded in 3 cases. I8 down plasma viscosity measurement, a typical sign of high viscosity integrated units (Hvs) 8 down, 1O patients with impaired renal function. Annex. 12 Methods venipuncture arm or arms intermittent and continuous flow centrifugation, equal amount of input and output of the constant exchange of body fluids, the centrifuge speed 1600r/rain, whole blood flow velocity (25-35) / rain, blood and anti- coagulant ACD-A ratio of 11: l. Replacement fluid first with saline, glucose solution, low molecular weight dextran, 706 on behalf of the plasma, hydroxyethyl starch, and then past the application of fresh plasma and dried plasma. PE added after the end of albumin. The amount of PE per 1000 ~ 3500ml. Intensive care operation. Time symptoms were recorded, blood pressure, pulse, heart rate and rhythm, and out of the liquid volume. Measured before and after replacement of blood, the clotting time, plasma viscosity, liver and kidney function, electrolytes, A / G, immune globulin. Some patients also isolated from the plasma bag to do the appropriate checks each down range separation of 1 ~ I4 times to 2 or 3 times as many, PE total of 119 times. 2 Results 2l effect shortly after PE treatment to remove the serum M protein and light chain elements, and thus reduce the plasma viscosity, blood urea nitrogen (BUN) the gradual recovery of renal function was improved. Clinical evaluation of platform, but still need to end chemotherapy,[link widoczny dla zalogowanych], according to national standards assessment. 43 cases with long-term follow-up results of the 2 (】 cases. Of partial response (PR) plus cases, progress in 8 cases,[link widoczny dla zalogowanych], 2 cases. Especially for poor results using a variety of chemotherapy refractory cases of 6. Has achieved remarkable results . 1 case after 3 months of chemotherapy, sicker, dizziness, vision and hearing loss, lethargy, nose and gums keep bleeding, skin scattered bleeding points, plasma viscosity up to 646,[link widoczny dla zalogowanych], PE5 times matched sets of PR discharged chemotherapy . continued consolidation chemotherapy, the survival of 104 months __J. I patients with medical therapy, severe renal failure and anemia, BUN55.3mr ~ l / L, red blood cells in urine microscopy full field of vision, Hct12%. with Taiwan PE treatment, symptoms and signs significantly improved at discharge BUN normal -. 2.2MM complications of bleeding and infection rate of PE before the long-term repeated epistaxis, skin, gums, and retinal hemorrhage 41.I% (7 / 17), recurrent fever, upper respiratory tract and pulmonary infection 47% (8 / 27). PE were followed up for six months. only 1 case of retinal hemorrhage (52%), fever in 2 cases (children 7%) one. 2.3 people by physical characteristics of side effects, blood flow rate of more than 35ml /

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